• br User knowledge representation Various representation

  2020-02-19

  

  User knowledge representation Various representation approaches of user interests and preferences are proposed. In this work, we advocate a multidimensional semantic approach based on Bouzghoub et al. meta-model (Bouzeghoub and Kostadinov, 2005), depicted in Fig. 6, to model the user profile. The

• sirtuin activators Although the control group and tinnitus g

  2020-02-19

  

  Although the control group and tinnitus group do not significantly differ based on age, gender or hearing loss, a limitation of this study is that the control group is only group-matched, and not individually matched. Furthermore, we only tested hearing acuity in tinnitus patients via standard pure

• pak1 inhibitor br Collagens as new drivers of zebrafish tiss

  2020-02-19

  

  Collagens as new drivers of zebrafish tissue regeneration Contrary to mammals, zebrafish possess very high regeneration capacities and thereby represent a versatile model to study tissue and organ regeneration. Adult fish can fully reconstruct their brain, spinal cord, retina, kidney, liver, panc

• Cell swelling stimulates the release of

  2020-02-19

  

  Cell swelling stimulates the release of certain amino acids, in particular the non-protein amino LB Agar Miller taurine, via a pathway which has the characteristics of a channel rather than a carrier [54], [69]. Indeed, on the basis of pharmacological inhibition, it was suggested that volume-activa

• br Materials and methods br Data and statistical

  2020-02-19

  

  Materials and methods Data and statistical analysis The results were expressed as mean ± SEM. One-way analysis of variance (ANOVA), followed by Bonferroni\'s post-test or unpaired Student\'s t-test were used to determine significant differences between groups. The program used for statistical

• LP a levels are lowered by combined oral hormone therapy

  2020-02-19

  

  LP(a) levels are lowered by combined oral hormone therapy [80], [81], [82], [83], [84], whereas for most studies using transdermal HRT little or no changes have been observed [85], [86], [87]. Oral versus transdermal administration In general most markers are influenced in a similar way by oral

• Another clinical study indicated the daily consumption

  2020-02-19

  

  Another clinical study indicated the daily consumption of green tea with low concentrations of theanine and catechin would improve cognitive function (Ide et al., 2014). Further, in a double blind randomized clinical study involving 102 patients, the Hypericum extract was examined in terms of effica

• The work described by Dong Groves

  2020-02-19

  

  The work described by Dong, Groves, and co-workers (11) tested the hypothesis that neural stem cell development is sensitive to the clustering and mechanical state of the EphB4:ephrin-B2 receptor-ligand complex. They show that the quality of ephrin-B2-ligand signaling depends on its biophysical stat

• The interaction of EPAC with Rim has

  2020-02-19

  

  The interaction of EPAC2 with Rim1 has an important role in regulating neurotransmitter release. In addition, a recent EPAC2 knockout mice model study provides evidence that EPAC2 promotes transmitter release by maintaining the readily releasable pool (RRP) at mossy fiber (MF) synapses in the hippo

• It has been reported that PGE

  2020-02-19

  

  It has been reported that PGE2 increases expression of the survivin mRNA (Baratelli et al. 2005) and promotes the stabilization of the survivin protein in some tumor TNKS 49 australia (Krysan et al. 2003). However, it is unclear whether PGE2 affects the expression of survivin mRNA or promotes the s

• tipiracil sale PKA signalling in the nucleus was thought to

  2020-02-19

  

  PKA signalling in the nucleus was thought to be due to the translocation of the catalytic subunit upon activation from the tipiracil sale to the nucleus via diffusion [72]. However, a new understanding has emerged, as both the regulatory and catalytic subunits have been identified in the nucleus an

• Glucose Uptake Fluorometric Assay Kit mg Bcl functions as a

  2020-02-19

  

  Bcl6 functions as a transcription repressor via its N-terminal BTB domain and middle “second repression,” or “RD2” domain (Chang et al., 1996, Seyfert et al., 1996). A loss of function of the BCL6 BTB domain markedly impairs survival and proliferation of mature GC Glucose Uptake Fluorometric Assay K

• br Acknowledgments We thank our colleagues who

  2020-02-19

  

  Acknowledgments We thank our colleagues who have contributed to our understanding of the ursolic acid sale and the structure and function of APC/C, and apologize to those whose work we were unable to cite here. We thank J. Rajan Prabu for making the movies showing APC/C conformational changes. O

• br Introduction Concern has been raised over

  2020-02-19

  

  Introduction Concern has been raised over free estrogens (estrone [E1], 17ß-estradiol [E2] and 17α-ethynylestradiol [EE2] particularly) in the past decade due to their endocrine disrupting effects on environmental biota [1], [2]. Estrogens are excreted by vertebrates primarily as sulfate or glucu

• Introduction The number of patients with type diabetes is in

  2020-02-19

  

  Introduction The number of patients with type 2 diabetes is increasing globally, and has become a serious public health problem. Type 2 diabetic patients exhibit a higher risk of bone fracture [1]. In addition, clinical studies have indicated that increased fracture risk is associated with long-ter

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